Faculty | VetMed
Jeffrey Mason

Animal, Dairy & Vet Sciences
Reproductive Senescence, Orthopedics
Associate Professor
Contact Information
Office Hours: By Appointment
Go toOffice Location: BTEC 205
DialPhone: 435-797-0950
SendEmail: jeff.mason@usu.edu
Educational Background
Other, Regenerative Medicine, (Orthopedics, Gene therapy), University of Pennsylvania, School of Veterinary Medicine, 2013
N/A
PhD, Physiology, (Reproductive Biology), University of California, Davis, 2007 Dissertation
Utilizing Gonadal Manipulation to Elucidate the Influence of Reproductive Status on Survival, Body Weight and Pathology at Death in Mice
MS, Transgenics, University of California, Davis, 2001 Thesis
The effect of coating single- and double-stranded DNA with the recombinase A protein of Escherichia coli on transgene integration in mice.
Licensures & Certifications
Certification to Administer Naloxone, The University of Utah, 2021
Biography
We physiological and molecular methods to study ovarian aging and the influence of ovarian aging on female health and disease.
Teaching Interests
Physiology, Reproductive Physiology, Aging
Research Interests
Reproductive Physiology, Aging, Orthopedic Disease, rodent and large animal
Awards
Ad hoc 2021 NIH study section reviewer- Special Emphasis., 2021
NIH NICHDEditor, special edition, 2021
Gerontological Society of AmericaUSU CASS undergraduate research mentor of the year, 2021
USUAd hoc 2020 NIH study section reviewer- CMIR and ZRG1 EMNR-P., 2020
NIH NICHDManaging Judge, Biology and Medicine. Thomas Edison Charter School Science and Engineering Fair. Logan, UT. 2020., 2020
Thomas Edison Charter School- Managing Judge, Biology and Medicine. Thomas Edison Charter School Science and Engineering Fair. Logan, UT. 2019, 2020., 2019
Thomas Edison Charter School- Session moderator, North American Veterinary Regenerative Medicine Association, CA, 2018., 2018
North American Veterinary Regenerative Medicine Association- Session moderator, Large Animal Genetic Engineering Symposium, Park City, UT, 2018., 2018
Large Animal Genetic Engineering societySSR/FASEB Washington DC Scientific Research advocate, 2017., 2017
SSR/FASEB- Editorial Board member, Journal of Veterinary Science & Research, 2016., 2016
Journal of Veterinary Science & Research- Presenter, Equine stem cell therapy presentation, USU AAEP Equine Club, 2015., 2015
USU AAEP- Presenter, In vivo gene therapy presentation, USU AAEP Equine Club, 2015., 2015
USU AAEPEarly Career Reviewer program, 2014
NIHMentor, Merial Research Symposium for Veterinary Student Researchers (2014-2015)., 2014
MerialWoods Hole MBL, Molecular Biology of Aging Fellowship, 2011
Ellison Medical FoundationNIH-NIAMS Ruth L. Kirschstein National Research Service Award (NRSA) F32, 2010
NIH-NIAMSAmerican Physiological Society/NIDDK Minority Travel Fellowship, 2009
American Physiological Society/NIDDKAmerican Physiological Society Porter Physiology Development Award, 2007
American Physiological SocietyAustin Eugene Lyons Graduate Fellowship, 2007
University of California, DavisBusiness Development Fellow, 2005
University of California, DavisJastro-Shields Research Award, 2005
University of California, DavisAnimal Science Department McOmie Fellowship, 2004
Animal Science DepartmentAnimal Science Department McOmie Fellowship, 2003
Animal Science DepartmentChancellors Teaching Fellowship, 2003
University of California, DavisGraduate Research Mentorship, 2003
University of California, DavisJastro-Shields Research Award, 2002
University of California, DavisMcDonald J. Monroe Scholarship, 2002
University of California, DavisOutstanding Graduate Student Teaching Award, 2002
University of California, DavisTeaching Assistant Consultant Fellowship, 2002
University of California, DavisGamma Delta Chapter of Phi Sigma Society, 2001
American Physiological SocietyGraduate Opportunity/Cota-Robles Fellowship, 2001
University of California, DavisUniversity of California, Davis Foundation Fellowship, 2001
University of California, DavisA. K. Humphries Memorial Scholarship, 2000
University of California, DavisJastro-Shields Research Award, 2000
University of California, DavisNIH-IMSD Graduate Opportunity Fellowship, 1999
NIH-IMSDPublications - Abstracts
- Mason, J., (2019). Influence of Ovarian Function on Age Associated Changes in DNA Methylation in Mice. USU ADVS Summer Research Symposium
- Mason, J., (2019). Influence of ovarian function on age associated T-cell changes in mice. USU ADVS Summer Research Symposium
- Mason, J., (2019). Using the rAAV-TIMP3 vector for the improvement of osteoarthritis in an ovine model.
- Mason, J., (2019). Young ovarian somatic cell influence on neurodegenerative conditions associated with aging. USU ADVS Summer Research Symposium
- Mason, J., (2013). Decreased proteoglycan degradation in IL-1β-treated equine cartilage co-cultured with TIMP-3-transduced cells. Osteoarthritis and Cartilage
- Mason, J., (2013). Equine induced pluripotent stem cells: differentiation into osteogenic and chondrogenic lineages. ISSCR annual meeting proceedings *
- Mason, J., (2013). Wnt Gene Therapy Influenced Measures of Osteoarthritis. Journal of Orthopaedic Research, Transactions
- Mason, J., Gurda, B.L, (2013). In vivo gene therapy of the equine distal extremity with recombinant adeno-associated viral vectors for the treatment of laminitis.. Journal of Equine Veterinary Science *
- Mason, J., (2011). Pre-existing neutralizing antibodies to AAV capsids in large animals other than monkeys may confound in vivo gene therapy studies. Molecular Therapy
- Mason, J., (2009). When selecting an adeno-associated viral vector serotype, cell monolayer transduction efficiency does not accurately predict tissue transduction efficiency in equine synovial tissues. FASEB Journal
- Mason, J., (2005). Comparison of term placentas in cloned and control pregnancies in cattle.. REPRODUCTION FERTILITY AND DEVELOPMENT *
- Mason, J., (2003). Relative pattern of gene expression in placental and fetal tissues by in-vivo and in-vitro produced day 90 and day 180 bovine concepti. Theriogenology
- Mason, J., (2003). The effect of coating single- and double-stranded DNA with the recombinase A protein of Escherichia coli on transgene integration in mice. Transgenic Animal Research Conference IV, Tahoe City, CA. *
- Mason, J., (2001). Association of IGF-1 and -2 with fetal development at days 90 and 180 of gestation for in-vivo and in-vitro derived bovine pregnancies. Theriogenology
Publications - Books & Book Chapters
* Has not been peer reviewed
Publications - Fact Sheets
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Publications - Curriculum
* Has not been peer reviewed
Publications - Journal Articles
- Garcia, D.N, Saccon, T.D, Praidee, J., Rincón, J.A, Andrade, K.R, Rovani, M.T, Mandadori, R.G, Cruz, L.A, Barros, C.C, Masternak, M.M, Bartke, A., Mason, J., Schneider, A., (2019). Effect of caloric restriction and rapamycin on ovarian aging in mice. . Geroscience, doi: 10.1007/s11357-019-00087-x
- Habermehl, T.L, Parkinson, K.C, Hubbard, G.B, Ikeno, Y., Engelmeyer, J.I, Schumacher, B., Mason, J., (2019). Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice.. GeroScience, 41:1, 25-38.
- Habermehl, T.L, Parkinson, K.C, Mason, J., (2018). Germ Cell Depletion Influenced Neuromuscular, Sensory, Renal and Metabolic Function in Post Reproductive Female Mice. Obstetrics and Gynecology, doi: 10.29011/ 2577-2236/100031
- Peterson, R.L, Parkinson, K.C, Mason, J., (2017). Restoration of immune and renal function in aged females by re-establishment of active ovarian function. Reproduction, Fertility, and Development, 10:29, 2052-2059. doi: http://dx.doi.org/10.1071/RD16333
- Peterson, R.L, Parkinson, K.C, Mason, J., (2016). Manipulation of Ovarian Function Significantly Influenced Sarcopenia in Postreproductive-Age Mice. Journal of Transplantation, 2016
- Mason, J., Richardson, D.W, (2016). In vivo gene therapy of the equine distal extremity with recombinant adeno-associated viral vectors.. Musculoskeletal Regeneration, 2: e1418. , doi: doi: 10.14800/mr.1418.
- Mason, J., Gurda, B.L, Van Wettere, A., Engiles, J.B, Wilson, J.M, Richardson, D.W, (2015). Delivery and evaluation of recombinant adeno-associated viral vectors in the equine distal extremity for the treatment of laminitis. Equine Veterinary Journal, doi: 10.1111/evj. 12547
- Mason, J., Najarian, ., Anderson, G., Murray, J., Maga, E., (2006). The effect of coating single- and double-stranded DNA with the recombinase A protein of Escherichia coli on transgene integration in mice. .
- Bertolini, M., Mason, J., Beam, S., Carniero, G., Sween, M., Moyer, A., Famula, T., Sainz, R., Anderson, G., (2002). Morphology and morphometry of in-vivo and in-vitro produced bovine concepti from early pregnancy to term and association with high birth weights. Theriogenology, 58:5, 973-994.
- Mason, J., (2021). The interrelationship between female reproductive aging and survival.
- Mason, J., (2021). Specific PIWI-Interacting RNAs and Related Small Noncoding RNAs Are Associated With Ovarian Aging in Ames Dwarf (df/df) Mice. .
- Tyler, K.A, Habermehl, T.L, Mason, J., (2019). Manipulation of ovarian function influenced glucose metabolism in CBA/J mice.. Experimental gerontology, 126, 110686.
- Parkinson, K.C, Peterson, R.L, Mason, J., (2019). Germ Cell Depletion Influenced Neuromuscular, Sensory, Renal and Metabolic Function in PostReproductive Female Mice.
- Parkinson, K.C, Peterson, R.L, Mason, J., (2017). Cognition and Sensory Function Were Significantly Influenced by Restoration of Active Ovarian Function in Postreproductive Mice. Experimental Gerontology92, 28-33. doi: doi.org/10.1016/j.exger.2017.03.002
- Hill, R.J, Clement, H., Yeip, G., Merchant, S.S, Olsen, A.L, Stott, R.D, Van Wettere, A., Bressel, E., Mason, J., (2017). The Influence of Oblique Angle Forced Exercise in Surgically Destabilized Stifle Joints Is Synergistic with Bone, but Antagonistic with Cartilage in an Ovine Model of Osteoarthritis. Arthritis, doi: 10.1155/2017/7481619
- Mason, J., Gurda, B.L, Van Wettere, A., Engiles, J.B, Wilson, J., Richardson, D.W, (2017). Delivery and evaluation of recombinant adeno-associated viral vectors in the equine distal extremity for the treatment of laminitis.. Equine veterinary journal, 49:1, 79-86.
- Mason, J., Gurda, B.L, Hankenson, K.D, Harper, L.R, Carlson, C.S, Wilson, J.M, Richardson, D.W, (2016). Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity and osteophytosis in a skeletally mature rat model of osteoarthritis. Connective Tissue Research, 58:6, doi: http://dx.doi.org/10.1080/03008207.2016.1267153
- Mason, J., Terry, B.C, Merchant, S.S, Mason, H.M, Nazokkarmaher, M., Manipulation of Ovarian Function Significantly Influenced Trabecular and Cortical Bone Volume, Architecture and Density in Mice at Death. PLOS One, doi: 10.1371/journal. pone. 0145821
- Mason, J., (2013). Multiple recombinant adeno-associated viral vector serotypes display persistent in vivo gene expression in vector-transduced rat stifle joints. , 3:24, 185-194.
- Mason, J., (2013). Resistance to genotoxic stresses in Arctica islandica, the longest-living noncolonial animal: Is extreme longevity associated with a multi-stress resistance phenotype?. Journals of Gerontology-Series A Biological Sciences, 68(5), 521-529.
- Simonaro, C.M, Mason, J., Mason, J., (2013). Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells. PLOS ONE, 8:4, doi: 10.1371/journal.pone.0062715
- Simonaro, C.M, Mason, J., Mason, J., (2013). Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells. PLOS ONE, 8:4, doi: 10.1371/journal.pone.0062715
- Mason, J., Vandenberghe, L., Xiao, R., Wilson, ., Richardson, D., (2012). Influence of serotype, cell type, tissue composition, and time after inoculation on gene expression in recombinant adeno-associated viral vector–transduced equine joint tissues. American Journal of Veterinary Research, 73:8, 1178-1185.
- Mason, J., Cargill, S., Anderson, G., Carey, J., (2011). Transplantation of young ovaries restored cardioprotective influence in postreproductive-aged mice. Aging Cell, 10:3, 448-456.
- Mason, J., (2010). Ovarian status influenced the rate of body-weight change, but not the total amount of body-weight gained or lost in female CBA/J mice. Experimental Gerontology, 6:45, 435-441.
- Mason, J., (2009). Transplantation of young ovaries to old mice increased survival and life span in transplant recipients. Journals of Gerontology-Series A Biological Sciences, 64:12, 1207-1211.
- Mason, J., (2007). Perinatal physiology in cloned and normal calves: Hematologic and biochemical profiles.. Cloning Stem Cells, 9, 83-96.
- C.A, B., M., B., Mason, J., Moyer, A., Hoffert, K., Petkov, S., Famula, T., Angelos, J., George, L., Anderson, G., (2007). Perinatal physiology in cloned and normal calves: Physical and clinical characteristics. Cloning Stem Cells, 9, 63-82.
- Mason, J., (2005). Effect of the nuclear-donor cell lineage, type, and cell donor on development of somatic cell nuclear transfer embryos in cattle. Cloning Stem Cells, 7:4, 238-54.
- Mason, J., (2004). Evidence of increased substrate availability to in vitro-derived bovine foetuses and association with accelerated conceptus growth. Reproduction, 128, 341-354.
Professional Journal
* Has not been peer reviewed
Publications - Literary Journal
* Has not been peer reviewed
Publications - MultiMedia
Video
Web
* Has not been peer reviewed
Publications - Technical Reports
* Has not been peer reviewed
Publications - Translations & Transcripts
Publications - Other
- Mason, J., (2016). Young ovaries rejuvenate older mice and extend their lifespan.. New Scientist *
Magazine/Trade Publication
* Has not been peer reviewed
Scheduled Teaching
VM 7520 - Veterinary Physiology II, Spring 2022
VM, ADVS 7519 - Veterinary Physiology I, Fall 2021
VM 7520 - Veterinary Physiology II, Spring 2021
VM 7519 - Veterinary Physiology I, Fall 2020
VM 7520 - Veterinary Physiology II, Spring 2020
ADVS, BIOL 6630, 5630 - Endocrinology, Fall 2019
ADVS, VM 7519 - Veterinary Physiology I, Fall 2019
HONR 4900 - Honors Thesis/Capstone, Spring 2019
HONR 4900 - Honors Thesis/Capstone, Spring 2019
HONR 4900 - Honors Thesis/Capstone, Spring 2019
VM 7520 - Veterinary Physiology II, Spring 2019
VM 7519 - Veterinary Physiology I, Fall 2018
VM 7520 - Veterinary Physiology II, Spring 2018
VM 7519 - Veterinary Physiology I, Fall 2017
ADVS 7520 - Veterinary Physiology II, Spring 2017
VM 7520 - Veterinary Physiology II, Spring 2017
VM/ADVS7519 - Physiology I, Fall 2016
ADVS, VM 7519 - Veterinary Physiology I, Fall 2016
ADVS, VM 7520 - Veterinary Physiology II, Spring 2016
VM 7519 - Veterinary Physiology I, Fall 2015
VM 7520 - Veterinary Physiology II, Spring 2015
VM 7519 - Physiology I, Fall 2014
ADVS 2200 - , Spring 2014
Graduate Students Mentored
Tracy Habermehl, Animal, Dairy & Vet Sciences, July 2017
Crystal Collier, Animal, Dairy & Vet Sciences, September 2016