Brett Hurst

Animal, Dairy & Vet Sciences

Research Assistant Professor


Brett Hurst

Contact Information

Office Location: VSB 309
Phone: 435-797-1631
Email: brett.hurst@usu.edu

Educational Background

PhD, Animal Health & Disease, (Virology), Utah State University, 2018
A Mouse Model of Enterovirus D68 Demonstrating Acute Flaccid Paralysis and Response to Antiviral Therapies
MS, Bioveterinary Science, (Virology), Utah State University, 2012
In Vitro and In Vivo Comparison of the Pathogenicity of Four Influenza A Virus Strains
BS, Microbiology, (Chemistry), Weber State University, 2006

Biography

Dr. Hurst has worked for the Institute for Antiviral Research since 2006. He completed his M.S. working with influenza virus and his Ph.D. with Enteroviruses.

Teaching Interests

Virology
Biotechnology
Antiviral Therapies

Research Interests

Evaluation of antiviral therapies in cell culture an animal models of disease. I have a particular focus on influenza viruses, picornaviruses, and of course coronaviruses. Our focus at the Institute for Antiviral Research is to recognize emerging viral infectious diseases and establish cell culture and animal models to evaluate therapies and vaccines.

Awards

1st Place Ph.D. Oral Presentation, 2018

Animal, Dairy, and Veterinary Science Student Research Symposium

Poster Award, 2018

International Society for Antiviral Research


Publications | Journal Articles

Academic Journal

  • Honda-Okubo, Y., Sakala, I.G, Andre, F., Tarbet, B., Hurst, B., Petrovsky, N., (2023). An Advax-CpG55.2 adjuvanted recombinant hemagglutinin vaccine provides immunity against H7N9 influenza in adult and neonatal mice. Vaccine, 5592-5602. doi: 10.1016/j.vaccine.2023.07.061
  • Lane, T.R, Fu, J., Sherry, B., Tarbet, B., Hurst, B., Riabova, O., Kazakova, E., Egorova, A., Clarke, P., Leser, J.S, Frost, J., Rudy, M., Tyler, K.L, Klose, T., Volobueva, A.S, Velyaevskaya, S.V, Zarubaev, V.V, Kuhn, R.J, Makarov, V., Ekins, S., (2023). Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5. Antiviral Research, doi: 10.1016/j.antiviral.2023.105654
  • Spengler, J.R, Carter, K., Delang, L., Durantel, D., Gowen, B., Herrero, L.J, Hurst, B., Janeba, Z., Jordan, R., Luo, D., Meier, C., Moffat, J., Rocha-Pereira, J., Seley-Radtke, K.L, Welch, S.R, Schang, L.M, (2023). Meeting report: 36th International Conference on Antiviral Research in Lyon, France - March 13-17, 2023. Antiviral Research, 217, 105678. doi: https://doi.org/10.1016/j.antiviral.2023.105678
  • Peterson, C.J, Hurst, B., Evans, W., Van Wettere, A., Gibson, S.A, Smee, D.F, Tarbet, B., (2023). Human IVIG treatment in a neurological disease model for Enterovirus A71 infection in 28-day-old AG129 mice. Virology580, 62-72. doi: 10.1016/j.virol.2023.02.002
  • Owen, D.R, Allerton, C.M, Anderson, A.S, Aschenbrenner, L., Avery, M., Berritt, S., Boras, B., Cardin, R.D, Carlo, A., Coffman, K.J, Dantonio, A., Di, L., Eng, H., Ferre, R., Gajiwala, K.S, Gibson, S.A, Greasley, S.E, Hurst, B.L, Kadar, E.P, Kalgutkar, A.S, Lee, J.C, Lee, J., Liu, W., Mason, S.W, Noell, S., Novak, J.J, Obach, R.S, Ogilvie, K., Patel, N.C, Petterson, M., Rai, D.K, Reese, M.R, Sammons, M.F, Sathish, J.G, Singh, R.S, Steppan, C.M, Stewart, A.E, Tuttle, J.B, Updyke, L., Verhoest, P.R, Wei, L., Yang, Q., Zhu, Y., (2021). An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science, 374:6575, 1586-1593. doi: 10.1126/science.abl4784

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Publications | Other

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Teaching

, Fall 2023
USU 1010 - University Connections, Fall 2023
ADVS, VM 7535 - Veterinary Virology, Fall 2023
ADVS 3200 - Ethical Issues in Genetic Engineering and Biotechnology, Spring 2023
, Fall 2022
ADVS 5650, 6650 - Science Communication, Fall 2022
USU 1010 - University Connections, Fall 2022
ADVS, VM 7535 - Veterinary Virology, Fall 2022
ADVS, PHIL 3200, 4530 - Ethics and Biotechnology, Spring 2022
ADVS, VM 7535 - Veterinary Virology, Fall 2021
ADVS, PHIL 3200, 4530 - Ethical Issues in Genetic Engineering and Biotechnology, Spring 2021
ADVS, PHIL 3200, 4530 - Ethics and Biotechnology, Spring 2020

Graduate Students Mentored

Kirsten Boardman, Animal, Dairy & Vet Sciences, September 2023
Scott Gibson, Animal, Dairy & Vet Sciences, January 2023
Zoe Taylor, Animal, Dairy & Vet Sciences, August 2021 - September 2023
Scott Gibson, Animal, Dairy & Vet Sciences, August 2019 - August 2022